Game-changer fix for injection site reactions with MOTS-C
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Been struggling with some pretty gnarly red, itchy welts every time I inject MOTS-C. Like, full-on raised knots that looked bad enough that I had to stop pinning my stomach entirely — not exactly a great look heading into summer. Moved everything to my glutes instead just to hide the mess.
I tried going the antihistamine route with Zyrtec and Benadryl and honestly got basically zero relief from either. Kept digging through old threads here looking for anything useful, and buried deep in someone's comment section I finally stumbled across something I hadn't seen mentioned before:
Spray Flonase directly on the injection site right after you pin.
I was skeptical but figured why not. Three days in now and I have had zero reaction — can't even locate where my last injection went in. Skin looks completely normal. Whoever dropped that tip in a random comment thread, you're a legend.
If you're dealing with the same histamine-type reactions to your peptides, this is absolutely worth trying.
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Worth noting that Flonase is actually a corticosteroid, and even though you're applying it topically it can still get absorbed systemically, so I'd keep any use short-term — two weeks max.
For the bumps and PIH I've had really good results using an ultrasonic with RF device over the injection spots, seems to do a solid job improving circulation in the area.
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Had the same issue — I'd heard people talking about injecting BPC/TB-500 directly into the problem area or even "in the knee," so I tried the back of my thigh and still got a little itchy spot. Switched to the belly and it was totally fine. Since I'm new to this I was also wondering what injecting "in the knee" actually means in practice, though I did read that since peptides are systemic it doesn't really matter where you inject and fatty areas like the belly work just as well.
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