Comparing 2mg Retatrutide vs 2mg Semaglutide — Which Comes Out Ahead?

[lazybear28]

Curious whether 2mg of retatrutide actually outperforms 2mg of semaglutide. Anyone have experience or insight on how the two stack up at that dose?

[ryan_lifts]

Ran sema for 2 months at 0.250mcg twice a week (Sundays and Wednesdays), dropped 3% body fat and actually gained some muscle on just a 200 calorie deficit — went from 228 down to 218. Almost done with my 2 months on reta at 1mg EOD and honestly it's been a completely different story, zero results and I'm hungry constantly, like genuinely starving the whole time. Same deficit, same foods, totally different experience.

[steph33]

Reta wins hands down in my opinion. I've actually been stacking it with a micro dose of tirz mid-week and it's been a solid combo.

[sunnylark63]

I was on liraglutide for a month and noticed some muscle wasting happening, which was a dealbreaker for me. Anyone know if retatrutide has the same issue with protein catabolism?

[SallyPep]

Honestly sema wasn't even close for me — bad side effects and I actually ended up gaining weight on it. Reta has been a completely different story, I'm down 48lbs and have managed to hold onto most of my muscle mass. No contest in my book.

[KyleT]

Honestly, just go with Reta — it's the clear winner here.